All functions |
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Generate a heatmap corresponding to an arbitrary aggregation level of a tree |
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Aggregate observed data based on a tree |
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Tree versions of diffcyt functions |
Wrapper applying an edgeR differential analysis workflow |
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Evaluate candidate levels and select the optimal one |
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Calculate false discovery rate (FDR) on a tree structure |
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Find the children of an internal node in a tree |
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Find branches that are non-overlapping with specified branches in a tree |
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Generate candidates for different thresholds |
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Extract data from a TreeHeatmap |
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Search for a target level on the tree via a specified score |
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Get information of candidates |
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Check whether nodes are contained in the same path from a leaf to the root in a tree |
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Calculate median values of markers for each cluster |
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Extract table with node-level DA/DS results |
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Parameter estimation for Dirichlet-multinomial distribution |
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Test for differential abundance using edgeR |
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Test for differential state using edgeR |
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Select branches meeting certain criteria |
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Simulate different scenarios of abundance change in entities |
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Generate a table of top-ranked entities (nodes) |
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Calculate true positive rate (TPR) on a tree structure |
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Generate weighted tree score accounting for the family effect |